What does non-seminoma mean?
Listen to pronunciation. (NON-seh-mih-NOH-muh) A type of cancer that begins in cells that form sperm or eggs. There are several types of nonseminoma tumors, including embryonal carcinoma, malignant teratoma, choriocarcinoma, and yolk sac tumor.
What is the most aggressive testicular tumor?
Nonseminomatous Germ Cell Tumors Embryonal carcinoma: present in about 40 percent of tumors and among the most rapidly growing and potentially aggressive tumor types. Embryonal carcinoma can secrete HCG or alpha fetoprotein (AFP).
What is a seminoma?
Listen to pronunciation. (SEH-mih-NOH-muh) A type of cancer that begins in germ cells in males. Germ cells are cells that form sperm in males or eggs in females. Seminomas occur most often in the testicle, but they may also occur in other areas of the body, such as the brain, chest, or abdomen.
Is seminoma a teratoma?
Germ cell neoplasms comprise germ cell neoplasia in situ (GCNIS), seminoma, and non-seminoma (NSGCT). The latter encompasses teratoma (postpubertal type), embryonal carcinoma, choriocarcinoma, yolk sac tumors (YSTs).
What a testicular tumor feels like?
A painless lump or swelling on either testicle. If found early, a testicular tumor may be about the size of a pea or a marble, but it can grow much larger. Pain, discomfort, or numbness in a testicle or the scrotum, with or without swelling. Change in the way a testicle feels or a feeling of heaviness in the scrotum.
Is seminoma curable?
Seminoma is a type of highly-curable cancer that originates in the germ cells of the testicle. A painless lump or swelling within the male testicle is usually the first sign of this cancer.
Can a teratoma be cancerous?
A malignant teratoma is a type of cancer consisting of cysts that contain one or more of the three primary embryonic germ layers ectoderm, mesoderm, and endoderm. Because malignant teratomas have usually spread by the time of diagnosis, systemic chemotherapy is needed.
What’s the difference between seminoma and nonseminomatous cancer?
Nonseminomatous tumors contain undifferentiated embryonic stem cells that can differentiate among different cell lines. These tumors commonly occur in the 20-30 age group and are much more aggressive than the seminomas. Embryonal carcinomas have a tubular or alveolar type of histological arrangement.
What’s the difference between nsgct and seminoma cancer?
There are several differences between seminomas and NSGCT, but the initial distinction is based on how the tumor looks under the microscope. Seminomas tend to grow and spread more slowly than NSGCT, although some seminomas can grow very rapidly. Subtypes of seminoma include:
What’s the difference between yolk sac and seminoma?
Yolk Sac Tumors. This is the commonest testicular tumor in infants and children who are below 3 years of age. Although there is a very good prognosis in the above age group, yolk sac tumors in adults can be life threatening. Histologically these tumors are nonencapsulated and have a mucinous appearance.
What to do if you have seminoma cancer?
Seminomas can secrete human chorionic gonadotropin (HCG) but do not secrete other tumor markers (see the section on tumor markers for more details). If seminoma spreads from the testicle, it is most often and best treated with chemotherapy and/or radiation. Surgery can be performed in some cases.