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What is an idiosyncratic reaction?

What is an idiosyncratic reaction?

Idiosyncratic drug reactions may be defined as adverse effects that cannot be explained by the known mechanisms of action of the offending agent, do not occur at any dose in most patients, and develop mostly unpredictably in susceptible individuals only.

What is an idiosyncratic drug response?

Idiosyncratic drug reactions, also known as type B reactions, are drug reactions that occur rarely and unpredictably amongst the population. This is not to be mistaken with idiopathic, which implies that the cause is not known.

What is a Type B drug reaction?

Type B Reactions Type B (bizarre) reactions are novel responses that are not expected from the known pharmacological actions of the drug. These are less common, and so may only be discovered for the first time after a drug has already been made available for general use.

When an abnormal and unusual reaction is produced by a drug it is known as?

An adverse drug reaction (ADR) is an injury caused by taking medication. ADRs may occur following a single dose or prolonged administration of a drug or result from the combination of two or more drugs.

What is an idiosyncratic person?

Idio is ancient Greek for “one’s own.” An idiosyncratic person is someone who does things in his own way. And the original meaning of idiot was basically “a regular Joe” — an ordinary person who keeps to himself. Definitions of idiosyncratic. adjective. peculiar to the individual.

What is idiosyncratic toxicity?

Idiosyncratic toxicity can occur when a convergence of risk factors, including drug exposure, tips the risk-benefit balance away from benefit and toward risk.

What is idiosyncrasy and allergy with example?

Idiosyncratic reactions are unpredictable and not explained by the pharmacologic properties of the drug. An example is the individual with infectious mononucleosis who develops a rash when given ampicillin.

What is idiosyncrasy in medication administration?

ABSTRACT. “Drug idiosyncrasy” refers to untoward reactions to drugs that occur in a small fraction of patients and have no obvious relationship to dose or duration of therapy.

Which medicine is harmful for brain?

Here are 10 of the top types of offenders.

  • Antianxiety drugs (Benzodiazepines)
  • Cholesterol-lowering drugs (Statins)
  • Antiseizure drugs.
  • Antidepressant drugs (Tricyclic antidepressants)
  • Narcotic painkillers.
  • Parkinson’s drugs (Dopamine agonists)
  • Hypertension drugs (Beta-blockers)

What is the most common type of adverse reaction?

The ten most common ADRs were constipation, nausea +/- vomiting, fatigue, alopecia, drowsiness, myelosuppression, skin reactions, anorexia, mucositis and diarrhoea. These ADRs have high-documented incidence rates and were also the ten most predictable ADRs in this study.

Which is an example of an idiosyncratic drug reaction?

“Drug idiosyncrasy” refers to untoward reactions to drugs that occur in a small fraction of patients and have no obvious relationship to dose or duration of therapy. The liver is a frequent target for toxicity. What are some examples of adverse drug events?

What is the meaning of the word idiosyncratic?

Besides, what is an idiosyncratic effect? Noun. idiosyncratic reaction (plural idiosyncratic reactions) (pharmacy, medicine) A reaction to a medication that is unusual and unpredictable, specific to a particular person. Unlike allergy, it can occur on first exposure to the medication; unlike a side effect, it affects only very few individuals.

Is it possible to predict an idiosyncratic reaction?

To be clear, an idiosyncratic reaction is abnormal in nature and is therefore not possible to predict who may develop one, when, or what specific form it will take ahead of time. While the good news is that idiosyncratic reactions aren’t all that common, the bad news is that when they do occur, many tend to be life-threatening in nature.

What does idiosyncratic toxicity mean in pharmacology?

In pharmacology, idiosyncrasy refers to an idiosyncratic reaction, which is an adverse effect to an agent, such as a drug, which does not occur in most patients who’ve used the same agent. In lay terms, when we say someone has a certain idiosyncrasy , we refer to a habit or mannerism that’s peculiar to that person.